Licht-im-Terrarium: Literaturdatenbank
Licht-im-Terrarium: Literaturdatenbank |
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Karu, T. I. (2008). Mitochondrial signaling in mammalian cells activated by red and near-ir radiation. Photochemistry and Photobiology, 84(5), 1091–1099. Added by: Sarina (23/03/2026, 09:37) |
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| Resource type: Journal Article DOI: 10.1111/j.1751-1097.2008.00394.x BibTeX citation key: anon2008d View all bibliographic details  |
Categories: General Creators: Karu Collection: Photochemistry and Photobiology |
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| Abstract |
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Abstract Mitochondrial signaling is an information channel between the mitochondrial respiratory chain and the nucleus for the transduction signals regarding the functional state of the mitochondria. The present review examines the question whether radiation of visible and near-IR (IR-A) radiation can activate this retrograde-type cellular signaling pathway. Experimental data about modulation of elements of mitochondrial retrograde signaling by the irradiation (mitochondrial membrane potential ΔΨm, reactive oxygen species ROS, Ca2+, NO•, pHi, fission-fusion homeostasis of mitochondria) are reviewed. The terminal enzyme of the mitochondrial respiratory chain cytochrome c oxidase is considered as the photoacceptor. Functions of cytochrome c oxidase as a signal generator as well as a signal transducer in irradiated cells are outlined.
Added by: Sarina |