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Windred, D. P., Burns, A. C., Rutter, M. K., Lane, J. M., Saxena, R., & Scheer, F. A. J. L., et al. (2025). Light exposure at night and cardiovascular disease incidence. JAMA Network Open, 8(10), e2539031–e2539031. 
Added by: Sarina (22/03/2026, 09:32)   
Resource type: Journal Article
DOI: 10.1001/jamanetworkopen.2025.39031
ID no. (ISBN etc.): 2574-3805
BibTeX citation key: anon2025a
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 Categories: General
Creators: Burns, Cain, Lane, Phillips, Rutter, Saxena, Scheer, Windred
Collection: JAMA Network Open		 Views: 12/22
Meine Sichtweise (Keine vollständige Zusammenfassung des Artikels! Meine Meinung muss nicht mit der Meinung der Autoren übereinstimmen! Bitte lesen Sie auch die Originalarbeit!)   

Zusammenfassung

  • 88 905 Erwachsene, älter als 40 aus der britischen Biobank bekamen für eine Woche ein Armband mit Lichtsensor
  • In der Datenbank erfasste Diagnosen aus dem Zeitraum Juni 2013 bis November 2022 wurden ausgewertet und mit den Lichtdaten korrelliert.
  • Die Personen mit den 10% hellsten Nächten hatten ein deutlich höheres Risiko verglichen mit den Personen mit den 50% dunkelsten Nächten für: koronare Herzkrankheit, Myokardinfarkt, Herzinsuffizienz, Vorhofflimmern und Schlaganfall.

Meinung:

  • Das Hormonsystem wird durch Licht gesteuert. Evolutionär ist es nachts - bis auf wenige Tage Ausnahme durch Vollmond - sehr dunkel. Licht in der Nacht bringt Prozesse im Körper durcheinander. 
  • Auch wenn hier keine Reptilien untersucht wurden, gehe ich davon aus, dass Nachtlicht (insbesondere blaues Nachtlicht, das besonders stark auf das Hormonsystem wirkt) nicht gesund ist. 

Added by: Sarina  Last edited by: Sarina
Abstract
Light at night causes circadian disruption, which is a known risk factor for adverse cardiovascular outcomes. However, it is not well understood of cardiovascular diseases.To assess whether day and night light exposure is associated with incidence of cardiovascular diseases, and whether associations of light with cardiovascular diseases differ according to genetic susceptibility, sex, and age.This prospective cohort study analyzed cardiovascular disease records across 9.5 years (June 2013 to November 2022) from UK Biobank participants who wore light sensors in a naturalistic setting. Data were analyzed from September 2024 to July 2025.Approximately 13 million hours of light exposure data, tracked by wrist-worn light sensors (1 week each), categorized into the 0 to 50th, 51st to 70th, 71st to 90th, and 91st to 100th percentiles.Incidence of coronary artery disease, myocardial infarction, heart failure, atrial fibrillation, and stroke after light tracking were derived from UK National Health Service records. Risks of cardiovascular diseases were assessed using Cox proportional hazards models (3 primary models adjusted at 3 levels) and reported as hazard ratios (HRs).A total of 88 905 individuals were included (mean [SD] age, 62.4 [7.8] years; 50 577 female [56.9\%]). Compared with individuals with dark nights (0-50th percentiles), those with the brightest nights (91st-100th percentiles) had significantly higher risks of developing coronary artery disease (adjusted HR [aHR], 1.32; 95\% CI, 1.18-1.46), myocardial infarction (aHR, 1.47; 95\% CI, 1.26-1.71), heart failure (aHR, 1.56; 95\% CI, 1.34-1.81), atrial fibrillation (aHR, 1.32; 95\% CI, 1.18-1.46), and stroke (aHR, 1.28; 95\% CI, 1.06-1.55). These associations were robust after adjusting for established cardiovascular risk factors, including physical activity, smoking, alcohol, diet, sleep duration, socioeconomic status, and polygenic risk. Larger-magnitude associations of night light with risks of heart failure (P for interaction = .006) and coronary artery disease (P for interaction = .02) were observed for females, and larger-magnitude associations of night light with risks of heart failure (P for interaction = .04) and atrial fibrillation (P for interaction = .02) were observed for younger individuals in this cohort.In this cohort study, night light exposure was a significant risk factor for developing cardiovascular diseases among adults older than 40 years. These findings suggest that, in addition to current preventive measures, avoiding light at night may be a useful strategy for reducing risks of cardiovascular diseases.
Added by: Sarina  
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