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Holick, M. F., MacLaughlin, J., Clark, MB., Holick, SA., Potts, JT,. Jr., & Anderson, R., et al. (1980). Photosynthesis of previtamin d3 in human skin and the physiologic consequences. Science, 210(4466), 203–205. 
Added by: Sarina (2011-08-29 11:50:56)   
Resource type: Journal Article
DOI: 10.1126/science.6251551
BibTeX citation key: Holick1980
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 Categories: Englisch = English
Keywords: Vitamin D = Vitamin D
Creators: Anderson, Blank, Clark, Elias, Holick, Holick, MacLaughlin, Parrish, Potts
Collection: Science		 Views: 2/1057
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Abstract
Photosynthesis of previtamin D3 can occur throughout the epidermis in the dermis when hypopigmented Caucasian skin is exposed to solar ultraviolet radiation. Once previtamin D3 is formed in the skin, it undergoes a temperature-dependent thermal isomerization that takes at least 3 days to complete. The vitamin D-binding protein preferentially translocates the thermal product, vitamin D3, into the circulation. These processes suggest a unique mechanism for the synthesis, storage, and slow, steady release of vitamin D3 from the skin into the circulation.
Added by: Sarina  
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