Lee, S., Kang, J.-H., Kim, C. H., Sung, E., Shin, H. C., & Cho, I. Y., et al. (2022). Investigation of the effect of ultraviolet light-emitting diodes exposure conditions on serum levels of 25-hydroxyvitamin d in female adults with vitamin d insufficiency. Korean J Fam Pract, 12(2), 110–115. Added by: Sarina (2022-09-20 15:05:03) Last edited by: Sarina (2022-09-20 15:06:07)
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Abstract
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- Background: To date, no research has been published on the effects of light-emitting diode (LED) devices emitting ultraviolet B (UVB) on serum 25-hydroxyvitamin D [25(OH)D] levels in humans. The objective of this study was to explore the efficacy and safety of UV-LED exposure by examining its effect on serum 25(OH)D levels in female adults with vitamin D insufficiency.
Methods: Among 13 female adults who visited the outpatient clinic of the Department of Family Medicine, Kangbuk Samsung Hospital, from June to July 2021, 9 female adults were included in the final analysis. Vitamin D insufficiency is defined as a serum 25(OH)D level of <30 ng/mL. The participants received UV-LED exposure three times per week for six weeks. Adverse reactions were assessed every two weeks after the first UV-LED exposure. The primary endpoint was the difference in serum 25(OH)D levels before and after six weeks of UV-LED exposure. Results: We found a statistically significant increase in serum 25(OH)D levels after six weeks of UV-LED exposure (P<0.001). Moreover, no severe adverse reactions were observed. Conclusion: Based on the results obtained, the UV-LED device could be a potentially safe and effective way to treat vitamin D insufficiency. - Keywords: Vitamin D; Females; Ultraviolet Light; Pilot Study
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