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Wee, R., & Gelder, R. V. N. (2004). Sleep disturbances in young subjects with visual dysfunction. Ophthalmology, 111(2), 297–302. 
Added by: Sarina (2013-01-22 15:21:42)   
Resource type: Journal Article
DOI: 10.1016/j.ophtha.2003.05.014
ID no. (ISBN etc.): 0161-6420
BibTeX citation key: Wee2004
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Categories: Englisch = English
Keywords: Chronobiologie = Chronobiology
Creators: Gelder, Wee
Collection: Ophthalmology
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Popularity index: 1.25%
Abstract
Purpose To determine whether the type of ophthalmic disease is predictive of sleep and wakefulness disturbances in young subjects with visual dysfunction. Design Prospective cohort study. Participants and controls Twenty-five subjects (ages 12–20) were recruited from the Missouri School for the Blind. Twelve controls with normal sight were recruited from a residential school. Methods Daily activity was monitored for 14 days using wrist actigraphy. Sleep and wakefulness measures were derived from actigraphy records by automated analysis. Visually impaired subjects were prospectively stratified by presence or absence of optic nerve disease. Main outcome measures Daytime napping and regularity of awakening time (wake-up time instability). Results Subjects with optic nerve disease napped in the daytime significantly more than other visually impaired children or normal sighted controls: 28.1±4.0 minutes per day (mean ± standard error) versus 11.9±2.4 minutes per day in equally visually impaired subjects with intact optic nerve function versus 6.2±2.2 minutes per day in subjects with normal sight (P<0.0001). These subjects also showed significantly more variable awakening times than the other groups. Logistic regression revealed that subjects with optic nerve disease are 9.1 times more likely to demonstrate daily napping of more than 20 minutes per day than equally blind subjects without optic nerve disease (95% confidence interval [CI] = 1.4–58.
Added by: Sarina  
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