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Lee, S., Kang, J.-H., Kim, C. H., Sung, E., Shin, H. C., Cho, I. Y., Oh, S., Lim, J.-S. & Kang, H. (2022) Investigation of the Effect of Ultraviolet Light-Emitting Diodes Exposure Conditions on Serum Levels of 25-Hydroxyvitamin D in Female Adults with Vitamin D Insufficiency. Korean J Fam Pract, 12 110–115. 
Added by: Sarina (20 Sep 2022 15:05:03 UTC)   Last edited by: Sarina (20 Sep 2022 15:06:07 UTC)
Resource type: Journal Article
DOI: 10.21215/kjfp.2022.12.2.110
BibTeX citation key: Lee2022a
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Categories: Englisch = English
Keywords: Leuchtdiode = Light-emitting Diode, Vitamin D = Vitamin D
Creators: Cho, Kang, Kang, Kim, Lee, Lim, Oh, Shin, Sung
Collection: Korean J Fam Pract
Views: 6/19
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Popularity index: 9%
Abstract
Background: To date, no research has been published on the effects of light-emitting diode (LED) devices emitting ultraviolet B (UVB) on serum 25-hydroxyvitamin D [25(OH)D] levels in humans. The objective of this study was to explore the efficacy and safety of UV-LED exposure by examining its effect on serum 25(OH)D levels in female adults with vitamin D insufficiency.
Methods: Among 13 female adults who visited the outpatient clinic of the Department of Family Medicine, Kangbuk Samsung Hospital, from June to July 2021, 9 female adults were included in the final analysis. Vitamin D insufficiency is defined as a serum 25(OH)D level of <30 ng/mL. The participants received UV-LED exposure three times per week for six weeks. Adverse reactions were assessed every two weeks after the first UV-LED exposure. The primary endpoint was the difference in serum 25(OH)D levels before and after six weeks of UV-LED exposure.
Results: We found a statistically significant increase in serum 25(OH)D levels after six weeks of UV-LED exposure (P<0.001). Moreover, no severe adverse reactions were observed.
Conclusion: Based on the results obtained, the UV-LED device could be a potentially safe and effective way to treat vitamin D insufficiency.
Keywords: Vitamin D; Females; Ultraviolet Light; Pilot Study
 

  
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