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Galkin, O. N. & Terenetskaya, I. P. (1999) ‘Vitamin D’ biodosimeter: basic characteristics and potential applications. Journal of Photochemistry and Photobiology B: Biology, 53 12–19. 
Added by: Sarina (20 Jan 2017 15:52:46 UTC)   Last edited by: Sarina (27 Apr 2021 08:00:33 UTC)
Resource type: Journal Article
DOI: http://dx.doi.org/10.1016/S1011-1344(99)00115-3
ID no. (ISBN etc.): 1011-1344
BibTeX citation key: Galkin1999
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Categories: Englisch = English
Keywords: Mathematik = Mathematics, UVBreitband = UVBroadband, Vitamin D = Vitamin D
Creators: Galkin, Terenetskaya
Collection: Journal of Photochemistry and Photobiology B: Biology
Views: 7/846
Views index: %
Popularity index: 3%
Meine Sichtweise (Keine vollständige Zusammenfassung des Artikels! Meine Meinung muss nicht mit der Meinung der Autoren übereinstimmen! Bitte lesen Sie auch die Originalarbeit!)    Wird eine Lösung von 7DHC in Ethanol mit Sonnenlicht bestrahlt, so wandelt sich ein Teil in die diversen bekannten Photoprodukte um. Die spektrale Transmission der Lösung ändert sich dabei und auch die Transmission bei 285 nm. Diese Änderung der Transmission kann als Dosimeter verwendet werden.
Added by: Sarina  
Abstract
The biologically important process of endogenous synthesis of vitamin D under {UV} solar irradiation is widespread in the biosphere and inherent to most animals and plants. A new method of biological dosimetry of {UV} radiation based on an in vitro model of vitamin D synthesis (‘D-dosimeter’) is discussed. Unlike the vast majority of biodosimeters, the action of which depends on the {UV} sensitivity of {DNA} and thus reflects damaging effects of {UV} radiation, the process of vitamin D synthesis is beneficial by its nature. To date, the complex network of photo- and thermoreactions of vitamin D synthesis in vitro is well understood, and an adequate mathematical model is available, ensuring a link between biological and physical units. Original spectral analysis of the multicomponent photoisomer mixture has been specially designed to provide the most effective use of the D-dosimeter in situ. Spectral selectivity (exceptional sensitivity of certain parameters to the spectral composition of {UV} radiation) extends the usefulness of the method.
  
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